EPCLUSA is a prescription medicine used to treat adults with chronic hepatitis C (Hep C) genotype 1-6 infection with or without cirrhosis (compensated).

EPCLUSA is a prescription medicine used to
treat adults with chronic hepatitis C (Hep C)
genotype 1-6 infection with or without cirrhosis
(compensated).

Important Safety Information

What is the most important information I
should know about EPCLUSA?

What is the most important
information I should know about
EPCLUSA?

EPCLUSA can cause serious side effects, including:

Hepatitis B virus reactivation: Before starting
EPCLUSA treatment, your healthcare provider will
do blood tests to check for hepatitis B infection. If
you have ever had hepatitis B, the hepatitis B virus
could become active again during and after
treatment with EPCLUSA. This may cause serious
liver problems including liver failure and death. If
you are at risk, your healthcare provider will monitor
you during and after taking EPCLUSA.

Hepatitis B virus reactivation:
Before starting EPCLUSA treatment,
your healthcare provider will do blood
tests to check for hepatitis B infection.
If you have ever had hepatitis B, the
hepatitis B virus could become active
again during and after treatment with EPCLUSA. This may cause serious liver
problems including liver failure and
death. If you are at risk, your
healthcare provider will monitor you
during and after taking EPCLUSA.

See complete Important Safety
Information below

When it comes to treating Hep C, you’re not alone. Watch stories from real people who have cured their chronic Hep C with EPCLUSA.

Brittany was surprised to find out that she could cure her Hep C with just one pill a day for 12 weeks on EPCLUSA.

Expand Transcript

BRITTANY:

I was diagnosed with Hep C a few years ago. I got it from a former boyfriend who was using drugs. That diagnosis devastated me.

TEXT ON-SCREEN:

Keep watching for Important Safety Information including Important Warning on Hepatitis B reactivation.

BRITTANY:

I thought that for the rest of my life I was going to have to take medication and wasn’t gonna be cured.

TEXT ON-SCREEN:

Brittany

Cured with EPCLUSA

Age 27

Cure means the Hep C virus was not detected in the blood 3 months after treatment ends.

BRITTANY:

Then my doctor said, “I want to start you on EPCLUSA. It has a high success rate of not just treating, but curing Hep C.” She told me it was gonna be one pill a day for twelve weeks. That was very surprising. I didn’t think that it would be so simple!

TEXT ON-SCREEN:

For adults with chronic Hep C genotype 1-6 without cirrhosis or with compensated cirrhosis. Prescription only.

BRITTANY:

We talked about any other kind of medications that I was taking that might interact with EPCLUSA. I take other medications for both my mental and physical health, and I was glad to learn that I didn’t have to stop taking my other medications.

TEXT ON-SCREEN:

EPCLUSA and certain other medicines may affect each other, or cause side effects. Talk to your doctor about all the medicines you take and if they will interact with EPCLUSA.

BRITTANY:

We also went over the possible side effects of EPCLUSA, like headache and tiredness. I really trusted my doctor. She seemed confident that EPCLUSA could help. I was so ready to get cured. I wanted to start treatment. I was like, “Let’s go!”.

TEXT ON-SCREEN:

Please visit EPCLUSA.com to view Important Facts about EPCLUSA, including Important Warnings on Hepatitis B reactivation.

BRITTANY:

So, from the time I was diagnosed to the time that I started treatment, it was only like a month.

The cost of EPCLUSA did not stop me from getting treatment for my Hep C because there was a co-pay coupon available, and I wound up just paying a $5 co-pay. That made it affordable for me. I don’t know that I could have done it any other way.

TEXT ON-SCREEN:

Pay as little as $5 per co-pay. Restrictions apply. See terms & conditions.

BRITTANY:

I took EPCLUSA one pill a day for 12 weeks. I could have taken it with or without food, but I took it with breakfast.

After I finished treatment, my test results came back negative. I was cured! It was like the biggest weight in the world was lifted right off my shoulders.

TEXT ON-SCREEN:

EPCLUSA’s 98% cure rate is based on studies of genotype 1-6 patients without cirrhosis or with compensated cirrhosis.

ANNOUNCER:

Before starting EPCLUSA, your doctor will test if you have had Hepatitis B, which may flare up and could cause serious liver problems, during and after treatment. Tell your doctor if you have had Hepatitis B, other liver or kidney problems, HIV, or other medical conditions…

TEXT ON-SCREEN:

If you have ever had Hepatitis B, it may flare up and could cause serious or life-threatening liver

problems.

ANNOUNCER:

…and all medicines you take, including herbal supplements. Taking amiodarone with EPCLUSA may cause a serious slowing of your heart rate. Common side effects include headache and tiredness.

TEXT ON-SCREEN:

EPCLUSA and certain medicines may affect each other, or cause side effects. Talk to your doctor

about all the medicines you take and if they will interact with EPCLUSA.

BRITTANY:

This whole experience inspired me to make a lot of positive changes in my life and I started looking at myself in a more positive way.

For a while, I volunteered at a rehab center and was able to help other young women who also had Hep C, and they didn’t know that there was a cure. They didn’t know that treatment was available, and they didn’t think it was possible for them or affordable for them.

My message for people in the Hep C community is: Don’t give up. There is still hope. You don’t need to feel shame. You are worthy of getting cured!

EPCLUSA is my kind of cure. Talk to your doctor. It could be your kind of cure, too.

TEXT ON-SCREEN:

EPCLUSA®

sofosbuvir / velpatasvir

400 mg/100 mg tablets

Pay as little as $5 per co-pay.

Restrictions apply. See terms & conditions.

Talk to your doctor or

Call 1-844-4-EPCLUSA.

Brittany found additional support by calling the EPCLUSA Education Line.

Expand Transcript

BRITTANY:

My doctor recommended EPCLUSA to treat my Hep C, and, before I started treatment, I had a lot of questions.

TEXT ON-SCREEN:

Brittany | Actual Patient

Age 27

For adults with chronic Hep C genotype 1-6 without cirrhosis or with compensated cirrhosis. Prescription only.

BRITTANY:

Calling the EPCLUSA Education line really helped me.

Between my doctor and the health educators, I was able to find out that yes, I could take EPCLUSA and still exercise at the gym, and yes, I could still take my other medications.

TEXT ON-SCREEN:

EPCLUSA and certain other medicines my affect each other, or cause side effects. Talk to your doctor about all the medicines you take and if they will interact with EPCLUSA.

BRITTANY:

I mentioned that I was concerned about the cost, and they told me about the EPCLUSA co-pay program.

I was able to get treatment for just a $5 co-pay.

TEXT ON-SCREEN:

Speak with an EPCLUSA Educator now

1-844-4-EPCLUSA (1-844-437-2587)

Pay as little as $5 per co-pay.

Restrictions apply. See terms & conditions.

ANNOUNCER:

TEXT ON-SCREEN:

If you have ever had Hepatitis B, it may flare up and could cause serious or life-threatening liver problems.

ANNOUNCER:

…and all medicines you take, including herbal supplements. Taking amiodarone with EPCLUSA may cause a serious slowing of your heart rate. Common side effects include headache and tiredness.

TEXT ON-SCREEN:

EPCLUSA and certain medicines may affect each other, or cause side effects.

BRITTANY:

Now I know there’s a lot of support for patients starting on EPCLUSA.

TEXT ON-SCREEN:

Please visit EPCLUSA.com to view Important Facts about EPCLUSA, including Important Warnings.

BRITTANY:

EPCLUSA is my kind of cure. Talk to your doctor. It could be your kind of cure, too.

TEXT ON-SCREEN:

EPCLUSA®

sofosbuvir/velpatasvir

400 mg /100 mg tablets

Pay as little as $5 per co-pay.

Restrictions apply. See terms & conditions.

Talk to your doctor or

Call 1-844-4-EPCLUSA.

Cure means the Hep C virus was not detected in the blood 3 months after treatment ends.

US-EPCC-0120 09/22

Hear how treatment was affordable for Frank with EPCLUSA.

Expand Transcript

FRANK:

When I found out that I could cure my Hep C, in my heart it was pure joy. I was just elated. But I wasn’t sure if I could afford the treatment…

TEXT ON-SCREEN:

FRANK

Actual patient

Please click on this video or visit EPCLUSA.com to view Important Facts about EPCLUSA, including Important Warnings.

FRANK:

…Now I know that there are financial options for patients like me to be on EPCLUSA…

TEXT ON-SCREEN:

For adults with chronic Hep C genotype 1-6 without cirrhosis or with compensated cirrhosis. Prescription only.

FRANK:

…I used a co-pay coupon and ended up only paying $5 co-pay. I felt great relief. My treatment wasn’t going to be a financial burden on my family.

TEXT ON-SCREEN:

Pay as little as $5 per co-pay. Restrictions apply. See terms & conditions.

ANNOUNCER:

Before starting EPCLUSA, your doctor will test if you have had Hepatitis B, which may flare up and could cause serious liver problems, during and after treatment.

Tell your doctor if you have had hepatitis B, other liver or kidney problems, HIV, or other medical conditions…

TEXT ON-SCREEN:

If you have ever had hepatitis B, it may flare up and could cause serious or life-threatening liver problems.

[Announcer VO]

…and all medicines you take, including herbal supplements. Taking amiodarone with EPCLUSA may cause a serious slowing of your heart rate.

Common side effects include headache and tiredness.

TEXT ON-SCREEN:

EPCLUSA and certain medicines may affect each other, or cause side effects.

FRANK:

Now I know that there is financial support for patients with Hep C.

EPCLUSA is my kind of cure. Talk to your doctor.

TEXT ON-SCREEN:

Cure means the Hep C virus was not detected in the blood 3 months after treatment ends.

TEXT ON-SCREEN:

EPCLUSA®

sofosbuvir/velpatasvir

400 mg/100 mg tablets

Pay as little as $5 per co-pay.

Restrictions apply. See terms & conditions.

Talk to your doctor or

Call 1-844-4-EPCLUSA

Frank was relieved that EPCLUSA was one pill a day and not injections.

Expand Transcript

FRANK:

Back in 2005, when I found out I had Hep C, it was harder for patients to get cured.

TEXT ON-SCREEN:

Please visit EPCLUSA.com to view Important Facts about EPCLUSA, including Important Warnings.

FRANK:

The only treatment for Hep C back then involved injections. But today, there’s EPCLUSA.

TEXT ON-SCREEN:

For adults with chronic Hep C genotype 1-6 without cirrhosis or with compensated cirrhosis. Prescription only.

FRANK:

EPCLUSA is a different kind of treatment regimen. One pill, once a day for 12 weeks.

TEXT ON-SCREEN:

Cure means the Hep C virus was not detected in the blood 3 months after treatment ends.

FRANK:

Boy, if I could take a pill or injection, I’m gonna pick the pill every—every time.

TEXT ON-SCREEN:

EPCLUSA’s 98% cure rate is based on studies of genotype 1-6 patients without cirrhosis or with compensated cirrhosis.

ANNOUNCER:

Before starting EPCLUSA, your doctor will test if you have had hepatitis B, which may flare up and could cause serious liver problems, during and after treatment. Tell your doctor if you have had hepatitis B, other liver or kidney problems, HIV, or other medical conditions…

TEXT ON-SCREEN:

If you have ever had hepatitis B, it may flare up and could cause serious or life-threatening liver problems.

ANNOUNCER:

…and all medicines you take, including herbal supplements. Taking amiodarone with EPCLUSA may cause a serious slowing of your heart rate. Common side effects include headache and tiredness.

TEXT ON-SCREEN:

EPCLUSA and certain medicines may affect each other, or cause side effects.

FRANK:

Now I know—EPCLUSA is different. With one pill a day, taking EPCLUSA is easy.

EPCLUSA is my kind of cure. Ask your doctor if it could be your kind of cure, too.

TEXT ON-SCREEN:

EPCLUSA®

sofosbuvir/velpatasvir

400 mg/100 mg tablets

Pay as little as $5 per co-pay.

Restrictions apply. See terms & conditions.

Talk to your doctor or

Call 1-844-4-EPCLUSA

When it came time to treat his Hep C, EPCLUSA fit into Butch’s routine.

Expand Transcript

TEXT ON-SCREEN:

EPCLUSA®

sofosbuvir / velpatasvir

400mg/100 mg tablets

For adults with chronic Hep C genotype 1-6 without cirrhosis or with compensated cirrhosis. Prescription only.

Keep watching for Important Safety Information including Important Warning on Hepatitis B reactivation.

BUTCH:

My name is Butch. I’m from Louisville, Kentucky, and I manage a warehouse. I’m as happy as can be when I’m at home, hanging out with my family and friends, washing my car, cutting my grass, stuff like that.

I was diagnosed with Hepatitis C back in, I believe, 2010. First, my wife was diagnosed with it and, um, when she came home, she explained to me what the doctor told her, and it’d be a good idea for me to go in and be tested. So, um, I made an appointment, and I went in…

TEXT ON-SCREEN:

Butch

Cured with EPCLUSA

Cure means the Hep C virus is not detected in the blood when measured three months after treatment is completed.

BUTCH:

…and I was tested, and I seen that I had Hepatitis C, too.

I tried Interferon as part of my treatment for Hep C. That was the standard back then. But, um, the side effects were too much for me, and I had to stop taking it.

After I failed Interferon, I was thinking there’s nothing that can be done, and it was something that I was just going to have to live with.

It was always in the back of my mind. With my Hep C, I had no symptoms, but, um, I was scared I might pass it on to one of my kids, and I worried that it might catch up to me as I got older. I knew I needed to take care of myself and treat my Hep C.

Then, one day I started seeing ads for EPCLUSA. That got me thinking. I should get treatment for my Hep C, and I shouldn’t put it off. I went to the doctor. They did blood work. I found out I was genotype 2.

My doctor said EPCLUSA would be a good option for me because it treats all types of chronic Hep C.

TEXT ON-SCREEN:

Before starting EPCLUSA, your doctor will test if you have had hepatitis B, which may flare up, and could cause serious liver problems during and after treatment.

BUTCH:

He said it could be taken with or without food and I only had to take it for 12 weeks, rather than injections with Interferon. I was happy to know EPCLUSA was not like Interferon.

I have a great relationship with my doctor, and I really trusted his opinion.

My doctor and I talked about any other kind of medications that I was taking that might interact with EPCLUSA.

TEXT ON-SCREEN:

EPCLUSA and certain medicines may affect each other, or cause side effect.

BUTCH:

We also went over the common side effects of EPCLUSA like headache and tiredness.

After all that time, I wanted to be cured of my Hep C and put it behind me.

The cost of treatment almost turned me away from it. With the co-pay coupon, it made it affordable for me.

TEXT ON-SCREEN:

Pay as little as $5 per co-pay.

Restrictions apply. See terms & conditions.

BUTCH:

I took EPCLUSA every morning right after I got out of the shower. I took it with my other medications.

TEXT ON-SCREEN:

Talk to your doctor about any other medicines you are taking.

BUTCH:

For me, it was easy to remember to take one more pill as part of my routine.

TEXT ON-SCREEN:

Store EPCLUSA tablets below 86°F (30°C).

BUTCH:

Then, I had my follow up appointment, and the blood work showed that it was completely gone. I was cured of my Hep C.

TEXT ON-SCREEN:

EPCLUSA’s 98% cure rate is based on studies of genotype 1-6 patients without cirrhosis or with compensated cirrhosis.

BUTCH:

It was a big relief. It was like a burden off my shoulders. I mean, I was probably the happiest guy around town. I was like, “Why didn’t I do this sooner?” I wish I would have cured my Hep C with EPCLUSA sooner.

My wife was cured with EPCLUSA as well. We were totally thrilled!

TEXT ON-SCREEN:

Tee

Cured with EPCLUSA

ANNOUNCER:

Before starting EPCLUSA, your doctor will test if you have had hepatitis B, which may flare up and could cause serious liver problems, during and after treatment.

Tell your doctor if you have had hepatitis B, other liver or kidney problems, HIV, or other medical conditions…

TEXT ON-SCREEN:

If you have ever had hepatitis B, it may flare up and could cause serious or life-threatening liver problems.

ANNOUNCER:

…and all medicines you take, including herbal supplements. Taking amiodarone with EPCLUSA may cause a serious slowing of your heart rate.

Common side effects include headache and tiredness.

TEXT ON-SCREEN:

EPCLUSA and certain medicines may affect each other, or cause side effects.

BUTCH:

I want people to know that you can do something about Hep C.

No matter how long ago you was diagnosed – even if you don’t have any symptoms – you shouldn’t put it off.

EPCLUSA was definitely my kind of cure.

Ask your doctor if EPCLUSA could be your kind of cure.

TEXT ON-SCREEN:

Talk to your doctor or call 1-844-4-EPCLUSA (1-844-437-2587) for more information.

EPCLUSA®

sofosbuvir / velpatasvir

400 mg/100 mg tablets

Please see Important Facts for Important Warning on hepatitis B reactivation on EPCLUSA.com.

EPCLUSA, the EPCLUSA logo, GILEAD and the GILEAD logo are trademarks of Gilead Sciences, Inc., or its related companies. All other trademarks referenced herein are the property of their respective owners.

At first, Chris was uncertain about Hep C treatment. Then he was cured with EPCLUSA.

Expand Transcript

TEXT ON-SCREEN:

EPCLUSA®

sofosbuvir / velpatasvir

400 mg/100 mg tablets

CHRIS:

I’m Chris. I’m from South Carolina, born and raised. I’m a father of two, happily married. I work in an auto shop, mainly oil changes and stuff like that.

I was diagnosed with hepatitis C in February of 2004. I absolutely blame myself for it. You know, I’d been using intravenous drugs for quite some time.

After I got clean, things were going better, but I knew that it would catch up to me one day, and I was scared I wouldn’t get to see my kids graduate high school.

I eventually went and seen a doctor. He told me, he said, “Your liver is in pretty bad shape. We need to get you on some kind of treatment now.” And that’s when he told me about EPCLUSA.

TEXT ON-SCREEN:

EPCLUSA is a prescription medicine used to treat adults with chronic (lasting a long time) hepatitis C (Hep C) genotype 1, 2, 3, 4, 5, or 6 infection with or without cirrhosis (compensated). In those with advanced cirrhosis (decompensated), EPCLUSA is used with ribavirin. EPCLUSA was approved by the FDA IN 2016.

CHRIS:

My doctor said that EPCLUSA treats all main types of chronic Hep C, that I’d only have to take one pill once a day for 12 weeks, and that I could take it with or without food.

TEXT ON-SCREEN:

For patients with advanced cirrhosis (decompensated), EPCLUSA is used with ribavirin.

CHRIS:

My doctor and I talked about any other kind of medications that I was taking that might interact with EPCLUSA. We also went over the common side effects of EPCLUSA like headache and tiredness.

TEXT ON-SCREEN:

Taking amiodarone with EPCLUSA may cause a serious slowing of your heart rate. Common side effects of EPCLUSA include headache and tiredness

CHRIS:

My doctor felt confident in recommending EPCLUSA. I was excited that I could take this medication and have a high hope for cure.

I would get up every morning, do my regular daily routine. At lunchtime, I would take one pill, and it was just really, really simple.

Three months after I finished treatment, I went to the doctor, and I found out that my hepatitis C was non-detectable. That meant that I’m cured, that my Hep C was finally gone!

TEXT ON-SCREEN:

Cure means the Hep C virus is not detected in the blood when measured three months after treatment is completed.

98% cure rate is based on studies of genotype 1-6 patients without cirrhosis or with compensated cirrhosis.

CHRIS:

It was such an amazing feeling! The tears afterwards were just sobbing tears of joy.

ANNOUNCER:

Before starting EPCLUSA, your doctor will test if you have had hepatitis B, which may flare up and could cause serious liver problems, during and after treatment.

TEXT ON-SCREEN:

If you have ever had hepatitis B, it may flare up and could cause serious or life-threatening liver problems.

ANNOUNCER:

Tell your doctor if you have had hepatitis B, other liver or kidney problems, HIV, or other medical conditions, and all medicines you take including herbal supplements. Taking amiodarone with EPCLUSA may cause a serious slowing of your heart rate.

Common side effects include headache and tiredness.

TEXT ON-SCREEN:

EPCLUSA and certain medicines may affect each other, or cause side effects.

CHRIS:

Moving forward without Hep C, I’ve got a new lease on life. It’s time to take the bull by the horns and do good things. I’m lucky to be where I’m at now in my life, and any day without Hep C is a blessing.

EPCLUSA was definitely my kind of cure.

TEXT ON-SCREEN:

Talk to your doctor or call 1-844-4-EPCLUSA (1-844-437-2587) for more information.

EPCLUSA®

sofosbuvir / velpatasvir

400 mg/100 mg tablets

Please see Important Facts for Important Warning on hepatitis B reactivation on EPCLUSA.com.

EPCC0433 02/20

Toby knew the importance of treating his Hep C quickly. He was cured with EPCLUSA.

Expand Transcript

TEXT ON-SCREEN:

EPCLUSA®

sofosbuvir / velpatasvir

400mg/100 mg tablets

For adults with chronic Hep C genotype 1-6 without cirrhosis or with compensated cirrhosis. Prescription only.

Keep watching for Important Safety Information including Important Warning on Hepatitis B reactivation.

TOBY:

I used to be a drug addict. I wanted to numb just the pain that I had inside me. Drugs got me in a lot of trouble. I spent at least 25 years of my life behind bars. So many years being in that little cage. My connection to the world was non-existent. I just felt like nobody seen me, nobody cared about me.

TEXT ON-SCREEN:

Toby

Cured with EPCLUSA

Cure means the Hep C virus is not detected in the blood when measured three months after treatment is completed.

TOBY:

That was extremely hard for me, you know? While I was serving my last sentence, I found out that I had Hepatitis C.

My eyes were definitely jaundice, yellow. I was extremely concerned, I–that it was gonna get worse, and I really wanted to get treatment. By that point, I had made the decision to stop using drugs, and I knew in my heart that I’m never going back to that lifestyle again. So I was ready for a cure.

After I got out, I seen my primary care physician. She referred me to a liver specialist. I saw the specialist through virtual appointment. It was really convenient for me. He looked at my labs, and he said that EPCLUSA was the right treatment for me. EPCLUSA treats all main types of chronic Hep C.

TEXT ON-SCREEN:

EPCLUSA is a prescription medicine used to treat adults with chronic (lasting a long time) hepatitis C (Hep C) genotype 1, 2, 3, 4, 5, or 6 infection with or without cirrhosis (compensated).

TOBY:

My doctor and I talked about any other kind of medications that I was taking that might interact with EPCLUSA.

TEXT ON-SCREEN:

EPCLUSA and certain medicines may affect each other, or cause side effects.

TOBY:

We also went over the common side effects of EPCLUSA like headache and tiredness. I asked my doctor if I could take EPCLUSA with my other medications, and he said yes. At that point, I was so anxious for treatment. I was so ready.

TEXT ON-SCREEN:

Taking amiodarone with EPCLUSA may cause serious slowing of your heart rate. Common side effects of EPCLUSA include headache and tiredness.

TOBY:

When I heard about EPCLUSA’s 98% cure rate, I felt so excited, and it gave me so much hope. I just can’t even put it into words.

TEXT ON-SCREEN:

EPCLUSA’s 98% overall cure rate is based on studies of genotype 1-6 patients without cirrhosis or with compensated cirrhosis.

TOBY:

I was concerned what the cost was going to be. I didn’t have a lot of money to spend on this treatment, and I was able to receive a copay coupon. Having that lower copay made it affordable for me.

TEXT ON-SCREEN:

Pay as little as $5 per co-pay. Restrictions apply. See terms & conditions.

TOBY:

So, my doctor called in the prescription to the specialty pharmacy. Not long after that, my first shipment of EPCLUSA came in the mail.

Fitting EPCLUSA into my daily routine was simple. I took one pill once a day without food, and I did it for 12 weeks.

TEXT ON-SCREEN:

EPCLUSA is only one pill, once a day, taken with or without food for 12 weeks.

TOBY:

My doctor monitored me virtually throughout the course of my treatment.

After treatment, I went and got more labs done. I got a phone call from the doctor’s office, and they said that I was cured. I got this new lease on life…

TEXT ON-SCREEN:

Before starting EPCLUSA, your doctor will test if you’ve had hepatitis B, which may flare up, and could cause serious liver problems during and after treatment.

TOBY:

…I mean, I was emotional. I just felt… man, it just felt so good that I’ve done all this work to change my life around, and now I don’t gotta worry about this Hepatitis C anymore. I felt like a nobody, and when–once I got cured, I felt like a somebody.

Looking back on everything that I’ve been through, my past and everything, getting cured for Hep C was not that hard. I never imagined that I’d ever reach this point.

TEXT ON-SCREEN:

If you want to learn more about EPCLUSA support and available resources, call the EPCLUSA Education

Line at 1-844-4-EPCLUSA.

TOBY:

There’s just so much to be grateful for. Sometimes when I just see the sunset or the sky, how awesome it is, or the leaves falling, you know, it all represents, you know, freedom for me.

I am free from my past, and I’m free from Hepatitis C. It feels unbelievable!

I feel, uhm, very validated in being a productive member of society. I got a great marriage. I got a great life. As a former addict, I know that I’ll always be working on my recovery, but uhm, I don’t have any desire to use drugs ever again.

If you’re living with Hep C and you’re ready to give that old life up, I’d say do not wait. Do not hesitate.

Get EPCLUSA. Talk to a doctor now. If I can do it, anybody can do it.

TEXT ON-SCREEN:

Toby’s story continues after the following Important Safety Information.

ANNOUNCER:

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about EPCLUSA?

EPCLUSA can cause serious side effects, including:

• Hepatitis B virus reactivation: Before starting EPCLUSA treatment, your healthcare provider will do blood tests to check for hepatitis B infection. If you have ever had hepatitis B, the hepatitis B virus could become active again during and after treatment with EPCLUSA. This may cause serious liver problems including liver failure and death. If you are at risk, your healthcare provider will monitor you during and after taking EPCLUSA

TEXT ON-SCREEN:

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about EPCLUSA?

EPCLUSA can cause serious side effects, including:

Hepatitis B virus reactivation: Before starting EPCLUSA treatment, your healthcare provider will do blood tests to check for hepatitis B infection. If you have ever had hepatitis B, the hepatitis B virus could become active again during and after treatment with EPCLUSA. This may cause serious liver problems including liver failure and death. If you are at risk, your healthcare provider will monitor you during and after taking EPCLUSA

ANNOUNCER:

What should I tell my healthcare provider before taking EPCLUSA?

Tell your healthcare provider about all of your medical conditions, including if you have ever had hepatitis B infection, liver problems other than hepatitis C infection, or a liver transplant; if you have kidney problems or are on dialysis; if you have HIV; or if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. It is not known if EPCLUSA will harm your unborn baby or pass into your breast milk.

Tell your healthcare provider and pharmacist about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. EPCLUSA and certain other medicines may affect each other, or may cause side effects.

TEXT ON-SCREEN:

What should I tell my healthcare provider before taking EPCLUSA?

• Tell your healthcare provider about all of your medical conditions, including if you have ever had hepatitis B infection, liver problems other than hepatitis C infection, or a liver transplant; if you have kidney problems or are on dialysis; if you have HIV; or if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. It is not known if EPCLUSA will harm your unborn baby or pass into your breast milk.

• Tell your healthcare provider and pharmacist about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. EPCLUSA and certain other medicines may affect each other, or may cause side effects.

[Announcer]

What are the possible side effects of EPCLUSA?

Serious side effects may also include slow heart rate (bradycardia). EPCLUSA, when taken with amiodarone (Cordarone®, Nexterone®, Pacerone®), a medicine used to treat certain heart problems, may cause slow heart rate. In some cases slow heart rate has led to death or the need for a pacemaker when amiodarone is taken with medicines containing sofosbuvir. Get medical help right away if you take amiodarone with EPCLUSA and get any of the following symptoms: fainting or near-fainting, dizziness or lightheadedness, not feeling well, weakness, extreme tiredness, shortness of breath, chest pains, confusion, or memory problems.

The most common side effects of EPCLUSA in adults include headache and tiredness.

These are not all the possible side effects of EPCLUSA. Call your doctor for medical advice about side effects.

TEXT ON-SCREEN:

What are the possible side effects of EPCLUSA?

Serious side effects may also include:

• Slow heart rate (bradycardia): EPCLUSA, when taken with amiodarone (Cordarone®, Nexterone®, Pacerone®), a medicine used to treat certain heart problems, may cause slow heart rate. In some cases slow heart rate has led to death or the need for a pacemaker when amiodarone is taken with medicines containing sofosbuvir. Get medical help right away if you take amiodarone with EPCLUSA and get any of the following symptoms: fainting or near-fainting, dizziness or lightheadedness, not feeling well, weakness, extreme tiredness, shortness of breath, chest pains, confusion, or memory problems.

• The most common side effects of EPCLUSA in adults include headache and tiredness.

These are not all the possible side effects of EPCLUSA. Call your doctor for medical advice about side effects.

ANNOUNCER:

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

TEXT ON-SCREEN:

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

TOBY:

EPCLUSA was definitely my kind of cure.

Ask your doctor if EPCLUSA can be your kind of cure.

TEXT ON-SCREEN:

Please see Important Facts for Important Warning on hepatitis B reactivation on EPCLUSA.com.

EPCLUSA®

sofosbuvir / velpatasvir

400 mg/100 mg tablets

Talk to your doctor or call 1-844-4-EPCLUSA (1-844-437-2587) for more information.

For years, Chris didn't know he had Hep C. Now, he's cured.

Expand Transcript

TEXT ON-SCREEN:

EPCLUSA®

Sofosbuvir/velpatasvir

400 mg/100 mg tablets

CHRIS:

I love being out on the water. There’s no email. There’s no phones. There’s no, uh, things to distract you. It’s so peaceful. And I like to get out any chance I can…

TEXT ON-SCREEN:

Keep watching for Important Safety Information including Important Warning on hepatitis B reactivation.

CHRIS:

…My name is Christopher. I’m the proud father of six, grandfather of two, and a Navy veteran.

Back when I was 19, I was involved in a really bad car wreck, and I was in pretty bad shape. I was hospitalized for a few days and received several blood transfusions. And, as a result of that, I acquired hepatitis.

Initially, I didn’t you know really think about hepatitis at all. I just thought it was a temporary thing.

Years later, I went to my doctor. We did some routine blood work, and the doctor came back into the room and said, “Were you aware that you had hepatitis C?” And that was the first time that I’d heard the term hepatitis C mentioned, and I remember specifically saying, “Well, how do we cure it? What do we need to do?”

And, at the time, they were basically saying that there really wasn’t any sure-fire method of curing Hep C, so I was extremely concerned. You know, liver disease, Hep C, that’s not a very pretty thing, and my biggest fear was that my kids or my wife would have to watch me, you know, go through that.

I started working with a specialist, and my diagnosis was confirmed–hepatitis C, genotype 1. It was explained to me that there are several types of Hep C and that genotype 1 was pretty common.

I tried a couple of different injectable treatments over the years. For me, going through those treatments was challenging, and ultimately, those treatments were not effective for me. I was told that I would be clear, but it didn’t work out that way. Both times, following both treatments, the virus came back, and we were back to square one.

By the time the virus reappeared following the second treatment, I was done. I just decided to live my life as best I could, knowing that Hep C would eventually catch up to me.

Then, one day, I heard about a treatment option called EPCLUSA. EPCLUSA treats all main types of chronic Hep C. For most people, it requires one pill a day, once a day for 12 weeks, and also it can be taken with or without food...

TEXT ON-SCREEN:

CHRIS:

…I admit I was somewhat skeptical because I’d been through two rounds of treatment previously. So, I really wanted to get all the information I could from my doctor. He walked me through what to expect, how treatment would work…

TEXT ON-SCREEN:

Before starting EPCLUSA treatment, your healthcare provider will do blood tests to check for hepatitis B infection. If you have ever had hepatitis B, the hepatitis B virus could become active again during and after treatment with EPCLUSA. This may cause serious liver problems including liver failure and death. If you are at risk, your healthcare provider will monitor you during and after taking EPCLUSA.

CHRIS:

…and that it has an overall cure rate of 98%. I didn’t think a true cure for Hep C was possible, but, um, I was cautiously optimistic that it might work for me.

TEXT ON-SCREEN:

In clinical studies, EPCLUSA had a high overall cure rate of 98% in patients with genotypes 1-6.

Cure means the Hep C virus is not detectable in the blood when measured three months after treatment is completed.

CHRIS:

My medical team and I talked about common side effects of EPCLUSA, like headaches and tiredness. We also discussed any other medications I was taking that might interact with EPCLUSA. And we talked about the blood tests that they would have to perform before I started treatment.

TEXT ON-SCREEN:

Taking amiodarone with EPCLUSA may cause a serious slowing of your heart rate. Common side effects of EPCLUSA include headache and tiredness.

CHRIS:

Ultimately, I felt like this was the right treatment for me, and we decided to move forward.

It was a simple treatment regimen: One pill once a day for 12 weeks. I made it part of my routine and took it the same time each day. Side effects were not a problem for me, but everyone’s experience with EPCLUSA may be different.

TEXT ON-SCREEN:

Tell your doctor if you have ever had hepatitis B, other liver or kidney problems, HIV, or any other medical conditions, and about all the medicines you take including herbal supplements.

CHRIS:

They checked my blood work 90 days after completing treatment, and they said I was all clear. They told me I was cured of Hep C. Personally, you know, I took it in, I understood what they meant by that, but given my personal experience, it just took me a little while to mentally take that in and to emotionally believe. It had been so difficult and such a journey. For somebody after 90 days to say, “You’re cured,” it was just unbelievable!

I had a conversation with my youngest son, and he said, “Dad, I look at you, and you’re like a phoenix rising.” (Laughs) And I said, “What do you mean by that?” And he said, “You’ve overcome so much, Dad. I’m so proud of you!” (chokes up) That was really, you know, good to hear.

TEXT ON-SCREEN:

Chris’ story continues after the following Important Safety Information.

ANNOUNCER

What is the most important information I should know about EPCLUSA?

EPCLUSA can cause serious side effects, including:

TEXT ON-SCREEN:

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about EPCLUSA?

EPCLUSA can cause serious side effects, including:

ANNOUNCER:

What should I tell my healthcare provider before taking EPCLUSA?

Tell your healthcare provider about all of your medical conditions, including if you have ever had hepatitis B infection or liver problems other than hepatitis C infection; if you have kidney problems or are on dialysis; if you have HIV; or if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. It is not known if EPCLUSA will harm your unborn baby or pass into your breast milk. If you take EPCLUSA with ribavirin, you should also read the ribavirin Medication Guide for important pregnancy-related information.

TEXT ON-SCREEN:

What should I tell my healthcare provider before taking EPCLUSA?

• Tell your healthcare provider about all of your medical conditions, including if you have ever had hepatitis B infection or liver problems other than hepatitis C infection; if you have kidney problems or are on dialysis; if you have HIV; or if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. It is not known if EPCLUSA will harm your unborn baby or pass into your breast milk. If you take EPCLUSA with ribavirin, you should also read the ribavirin Medication Guide for important pregnancy-related information.

ANNOUNCER:

What are the possible side effects of EPCLUSA?

Serious side effects may also include Slow heart rate (bradycardia). EPCLUSA, when taken with amiodarone (Cordarone®, Nexterone®, Pacerone®), a medicine used to treat certain heart problems, may cause slow heart rate. In some cases slow heart rate has led to death or the need for a pacemaker when amiodarone is taken with medicines containing sofosbuvir. Get medical help right away if you take amiodarone with EPCLUSA and get any of the following symptoms: fainting or near-fainting, dizziness or lightheadedness, not feeling well, weakness, extreme tiredness, shortness of breath, chest pains, confusion, or memory problems.

The most common side effects of EPCLUSA include headache and tiredness. Tell your healthcare provider if you have any side effect that bothers you or does not go away...

TEXT ON-SCREEN:

What are the possible side effects of EPCLUSA?

Serious side effects may also include:

ANNOUNCER:

…You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see Important Facts about EPCLUSA including Important Warning on EPCLUSA.com.

TEXT ON-SCREEN:

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see Important Facts about EPCLUSA including Important Warning on EPCLUSA.com.

ANNOUNCER:

What is EPCLUSA?

TEXT ON-SCREEN:

What is EPCLUSA?

CHRIS:

My wife, my family, my kids and I are looking forward to living a life free of Hep C and the worries and concerns with it, and we’re very grateful that, you know, I was able to be treated successfully and that I am cured today.

I want to inspire other people that are living with Hep C.

You know, it’s definitely curable, and so I encourage anybody that has Hep C to go talk to their doctor about effective treatments.

Even if you’ve had treatment before and it didn’t work out, there may be another option available for you today.

TEXT ON-SCREEN:

Cure means the Hep C virus is not detected in the blood when measured three months after treatment is completed.

CHRIS:

EPCLUSA was definitely my kind of cure.

Whatever your type, ask your doctor if EPCLUSA could be your kind of cure.

TEXT ON-SCREEN:

EPCLUSA®

Sofosbuvir/velpatasvir

400 mg/100 mg tablets

Please see Important Safety Information, including Important Warning on hepatitis B reactivation, on

EPCLUSA.com.

EPCC0472 03/20

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NOW I KNOWI wasn't the only one dealing with Hep C

Important Safety Information

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about EPCLUSA?

EPCLUSA can cause serious side effects, including:

What should I tell my healthcare provider before taking EPCLUSA?

What are the possible side effects of EPCLUSA?

What is EPCLUSA?

NOW I KNOW
I wasn't the only one dealing with Hep C